It remains a great challenge to overcome the intermittent and fluctuating sunlight for continuous photocatalytic fuels production. In this review, Joel and co-authors propose that persistent and memory-based photocatalysts, which efficiently operate under near zero light fluxes beyond sunset and during cloud intermittencies, are a potential solution to address and mitigate the challenge. Based on the idea of multivalent charge storage materials that allow charging during illumination and discharging to generate charge carriers upon post-illumination, this review describes examples of persistent photocatalysis systems, outlines the working mechanism, suggests strategies for performance optimization, proposes standardized Figures of Merit and discusses possible application scenes beyond solar fuels. See full story at AEM.